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Citrate Generic Name Sildenafil Viagra

citrate generic name sildenafil viagra

Sildenafil Citrate is one of the most effective drugs prescribed for the treatment of Erectile Dysfunction ED , aka male impotence. The drug was actually intended for treating the symptoms of pulmonary arterial hypertension; however, during the clinical studies, the drug was found to be extremely effective in treating the symptoms of ED. Sildenafil Citrate, simply put, improves erectile function in men so that they can make love satisfactorily.

Available under the brand name Viagra, Sildenafil Citrate also comes in various generic variants. Generic Sildenafil Citrate is as effective as Viagra and is available at a very reasonable price.

Sildenafil Citrate is available in various forms such as tablets, soft tabs, oral jellies, chewable tablets, sublingual tablets, and effervescent tablets.

Generic Sildenafil is available at an affordable price. Sildenafil Citrate, undeniably, is the best and safe drug for most men with ED. However, it is important to seek medical advice before using this prescription ED drug. A normal penile erection is a physiological process that is experienced by a man when he is sexually aroused.

Upon sexual stimulation, the brain sends signals to the penile organ through certain brain chemicals and hormones for an erection to happen during sexual stimulation. This physiological process is affected in impotency.

The penile organ fails to get enough blood for an erection due to certain physical conditions affecting the blood vessels. Sildenafil Citrate is the perfect drug for men who experience weak erections due to some underlying physical causes affecting the blood flow to the penile organ. The drug is essentially a PDE5 inhibitor, which means it inhibits the secretion of an enzyme PDE5 in order to elevate nitric oxide production.

With this pharmacological action, Sildenafil Citrate helps boost blood flow to the penile organ, as the blood vessels dilate and the muscles relax. In simple words, Sildenafil Citrate produces an erection by boosting blood flow to the penile organ during sexual stimulation. Synthetic medicines often produce certain side effects, and Sildenafil Citrate is no expectation. The drug may or may not produce side effects such as:. These are probable side effects.

One may experience other side effects that are not mentioned above. If you experience any unpleasant side effects such as chest pain, breathlessness, irregular pulse rates, or a prolonged erection, then immediately seek medical attention by visiting your nearest ER.

Sildenafil Citrate is contraindicated in men who are having end-stage illnesses related to liver or kidney, heart, brain, blood, and the penile organ.

The drug is also contraindicated in men who have been undergoing treatment with medications such as nitrates, alpha-blockers, protease inhibitors, and antidepressants. Children, teens, and women should stay away from Sildenafil Citrate. It helps by overcoming the main factor behind impotency i. It suppress PDE5 enzyme and increases levels of nitric oxide, a chemical compound essential for boosting blood flow. This medicinal drug takes some time to act, as it takes time to dissolve in the bloodstream.

It takes around 40 minutes to show its effect. This is medicine and not a hormone. Therefore, one needs to engage in sexual stimulation for making this medicine work.

Take this medication as prescribed by doctor. Consume it orally with sufficient water, and preferably 40 minutes before sexual activity. You need to take this medicine only when required; however, never take it more than once in span of 24 hours.

Dosage varies depending on the health conditions and age of an individual. Sildenafil citrate is available in 25 mg, 50 mg, and mg dosages. Doctor can tell you the perfect dosage depending on the medical conditions. There is even possibility that doctor would have prescribed a lower dosage.

Talk to your doctor in such instances. You can take this pill anytime as per convenience. However, be sure not to eat heavy or fatty meal before taking this medication. For great results, take this medicinal pill on empty stomach. The biological half-life of sildenafil citrate mg is three to four hours. Therefore, its total effect stays for approximately hours in body. During this phase, one can achieve multiple rigid erections on sexual stimulation.

Avoid fatty food, grapefruit, or heavy meals while taking treatment. Similarly, stay away from alcohol and tobacco, as these may nullify the effect of sildenafil citrate. Overdose of sildenafil citrate has harmful health complications, such as chest pain, impaired vision, rapid heartbeats, and heavy swelling. This is not a routine based medicinal therapy. You only need to consume its dosage while involving into sexual act.

This medicine is a drug and not a hormone. So there will be no effect on your body unless you go through sexual stimulation. So be carefree the medicine will not do any harm on your body in such accidental cases. This medicine is not additive. In addition, this medicine does not enhances sexual pleasure; therefore, you will not grow any dependency of this medicinal pill. Synthetic medications come with certain aftereffects. Side effects that one can go through after consuming sildenafil citrate are nausea, stomach upset, hot flashes, dizziness, headache, blur vision, and nasal congestion.

These are normally of mild and temporary nature. However, if they stay for longer duration, then visit a doctor. This medicinal drug is only formulated to men above 18 years of age. Therefore, a woman is strictly advisable to stay away from using sildenafil citrate dosage.

Men above 18 years of age suffering from erectile dysfunction can use this medicament. However, it is mandatory to get medical prescription prior to consuming medicament. This medication is not advisable for women and children. Along with this, men with medical conditions such as kidney or liver issues, low blood pressure, heart attack, anemia, and angina should not use this medicinal pill. This medicine does not go well with all the medicines.

Therefore, talk to a doctor regarding your ongoing treatments before starting this pill. Avoid taking this medicament if taking nitrates, alpha-blockers, protease inhibitors, antibiotics, antifungal, or antidepressants. You can Buy Sildenafil Citrate Online merely by providing medical prescription letter. You can also buy it at local drug store, but purchasing online can give you many benefits including variety of options, discounts, and doorstep delivery.

How to use the drug aptly? Sildenafil Citrate is a prescription ED drug so it should be used exactly as directed by your primary care physician. The recommended starting dose of the drug is 50 mg once in any hour period. It can be increased up to mg after seeking medical advice. It is essential to take the prescribed dose orally, approximately an hour before sexual activity; this gives enough time for the drug to assimilate in the body and exhibit its action. The drug has found be extremely effective when taken on empty stomach and with a full glass of water.

Avoid a fatty meal because it will delay the effectiveness. Stay away from certain substances that hamper the effects of Sildenafil Citrate, which include alcoholic beverages, illegal drugs, and grapefruits.

The duration of the effect of Sildenafil Citrate is four to six hours; during this period of time, you will able to get an erection during sexual stimulation and enjoy your sexual intercourse.

What precautions do I need to take? To be on a safer side, it is important to discuss certain issues with your doctor before using Sildenafil Citrate. You should inform your doctor about the pre-existing health issues that you have or have had in the past, such as: Nitrates, nitroglycerin, poppers Alpha-blockers or any antihypertensive agents Protease inhibitors, antimicrobials, or any antidepressants Sildenafil Citrate is known to cause a mild dizziness post-dosage; therefore, it is recommended not to indulge in any outdoor activity.

Exceeding the dose can lead to overdose, which can increase the risk of complications, so you must be careful with the dosage part. Store the tablets at room temperature, preferably away from heat, sunlight or moisture.

What are the side effects? The drug may or may not produce side effects such as: Who should not use the ED drug? What is Sildenafil Citrate? How does this medication help? Will Sildenafil Citrate act instantly? Does it starts working automatically? How to take this medication? What is perfect dosage? What should I do if medicine does not work first time? Should I use this pill with food or without? What is the duration of effect? Store it at room temperature in a dry airtight jar, away from direct sunlight and moisture.

What should I avoid?

Силденафил (силденафила цитрат) - Виагра Structural Biochemistry/Viagra (Sildenafil Citrate) - Wikibooks, open books for an open world

Citrate generic name sildenafil viagra

The penile organ fails to get enough blood for an erection due to certain physical conditions affecting the blood vessels. Sildenafil Citrate is the perfect drug for men who experience weak erections due to some underlying physical causes affecting the blood flow to the penile organ. The drug is essentially a PDE5 inhibitor, which means it inhibits the secretion of an enzyme PDE5 in order to elevate nitric oxide production.

With this pharmacological action, Sildenafil Citrate helps boost blood flow to the penile organ, as the blood vessels dilate and the muscles relax. In simple words, Sildenafil Citrate produces an erection by boosting blood flow to the penile organ during sexual stimulation. Synthetic medicines often produce certain side effects, and Sildenafil Citrate is no expectation.

The drug may or may not produce side effects such as:. These are probable side effects. One may experience other side effects that are not mentioned above. If you experience any unpleasant side effects such as chest pain, breathlessness, irregular pulse rates, or a prolonged erection, then immediately seek medical attention by visiting your nearest ER.

Sildenafil Citrate is contraindicated in men who are having end-stage illnesses related to liver or kidney, heart, brain, blood, and the penile organ. The drug is also contraindicated in men who have been undergoing treatment with medications such as nitrates, alpha-blockers, protease inhibitors, and antidepressants.

Children, teens, and women should stay away from Sildenafil Citrate. It helps by overcoming the main factor behind impotency i. It suppress PDE5 enzyme and increases levels of nitric oxide, a chemical compound essential for boosting blood flow. This medicinal drug takes some time to act, as it takes time to dissolve in the bloodstream. It takes around 40 minutes to show its effect. This is medicine and not a hormone. Therefore, one needs to engage in sexual stimulation for making this medicine work.

Take this medication as prescribed by doctor. Consume it orally with sufficient water, and preferably 40 minutes before sexual activity. You need to take this medicine only when required; however, never take it more than once in span of 24 hours. Dosage varies depending on the health conditions and age of an individual. Sildenafil citrate is available in 25 mg, 50 mg, and mg dosages. Doctor can tell you the perfect dosage depending on the medical conditions. There is even possibility that doctor would have prescribed a lower dosage.

Talk to your doctor in such instances. You can take this pill anytime as per convenience. However, be sure not to eat heavy or fatty meal before taking this medication. For great results, take this medicinal pill on empty stomach. The biological half-life of sildenafil citrate mg is three to four hours. Therefore, its total effect stays for approximately hours in body. During this phase, one can achieve multiple rigid erections on sexual stimulation. Avoid fatty food, grapefruit, or heavy meals while taking treatment.

Similarly, stay away from alcohol and tobacco, as these may nullify the effect of sildenafil citrate. Overdose of sildenafil citrate has harmful health complications, such as chest pain, impaired vision, rapid heartbeats, and heavy swelling. This is not a routine based medicinal therapy. You only need to consume its dosage while involving into sexual act.

This medicine is a drug and not a hormone. So there will be no effect on your body unless you go through sexual stimulation. So be carefree the medicine will not do any harm on your body in such accidental cases. This medicine is not additive. In addition, this medicine does not enhances sexual pleasure; therefore, you will not grow any dependency of this medicinal pill.

Synthetic medications come with certain aftereffects. Side effects that one can go through after consuming sildenafil citrate are nausea, stomach upset, hot flashes, dizziness, headache, blur vision, and nasal congestion. These are normally of mild and temporary nature.

However, if they stay for longer duration, then visit a doctor. This medicinal drug is only formulated to men above 18 years of age. Therefore, a woman is strictly advisable to stay away from using sildenafil citrate dosage. Men above 18 years of age suffering from erectile dysfunction can use this medicament. However, it is mandatory to get medical prescription prior to consuming medicament. This medication is not advisable for women and children. Along with this, men with medical conditions such as kidney or liver issues, low blood pressure, heart attack, anemia, and angina should not use this medicinal pill.

This medicine does not go well with all the medicines. Rare but serious adverse effects found through postmarketing surveillance include prolonged erections , severe low blood pressure , myocardial infarction heart attack , ventricular arrhythmias , stroke , increased intraocular pressure , and sudden hearing loss.

Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection. Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects.

Sildenafil should not be used if sexual activity is inadvisable due to underlying cardiovascular risk factors [21]. In one study, a mg dose was shown to cause no significant change in erectile quality, but did reduce the postejaculatory refractory time. Unprescribed recreational use of sildenafil and other PDE5 inhibitors is noted as particularly high among users of illegal drugs.

Plano, and Diego A. Golombek of Universidad Nacional de Quilmes , Argentina, for their discovery that sildenafil helps treat jet lag recovery in hamsters. Professional athletes have been documented using sildenafil, believing the opening of their blood vessels will enrich their muscles.

In turn, they believe it will enhance their performances. Acetildenafil and other synthetic structural analogs of sildenafil which are PDE5 inhibitors have been found as adulterants in a number of "herbal" aphrodisiac products sold over-the-counter.

However, at least one court case has resulted in a product being taken off the market. The US FDA has banned numerous products claiming to be Eurycoma longifolia that, in fact, contain only analogs of sildenafil.

Nitric oxide NO in the corpus cavernosum of the penis binds to guanylate cyclase receptors, which results in increased levels of cGMP, leading to smooth muscle relaxation vasodilation of the intimal cushions of the helicine arteries. This smooth muscle relaxation leads to vasodilation and increased inflow of blood into the spongy tissue of the penis, causing an erection.

Furchgott , Ferid Murad , and Louis Ignarro won the Nobel Prize in Physiology or Medicine in for their independent study of the metabolic pathway of nitric oxide in smooth muscle vasodilation. The molecular structure of sildenafil is similar to that of cGMP and acts as a competitive binding agent of PDE5 in the corpus cavernosum, resulting in more cGMP and better erections. Other drugs that operate by the same mechanism include tadalafil Cialis and vardenafil Levitra. Sildenafil is broken down in the liver by hepatic metabolism using cytochrome p enzymes, mainly CYP 3A4 major route , but also by CYP2C9 minor route hepatic isoenzymes.

The major product of metabolisation by these enzymes is N-desmethylated sildenafil, which is metabolised further. If taken with a high-fat meal, absorption is reduced; the time taken to reach the maximum plasma concentration increases by around one hour, and the maximum concentration itself is decreased by nearly one-third.

There are also mouth spray preparations of sildenafil for faster onset of action. The preparation steps for synthesis of sildenafil are: It was initially studied for use in hypertension high blood pressure and angina pectoris a symptom of ischaemic heart disease.

The first clinical trials were conducted in Morriston Hospital in Swansea. Numerous sites on the Internet offer Viagra for sale after an "online consultation", often a simple web questionnaire. Viagra is also informally known as "vitamin V", "the blue pill", or "blue diamond", as well as various other nicknames.

In February , it was announced that Boots , the UK pharmacy chain, would try over-the-counter sales of Viagra in stores in Manchester , England.

Men between the ages of 30 and 65 would be eligible to buy four tablets after a consultation with a pharmacist. While the sale remains subject to a consultation with a pharmacist, the other restrictions from the trial have been removed, allowing customers over the age of 18 to purchase an unlimited number of pills [59] The decision was made, in part, to reduce online sales of counterfeit and potentially dangerous erectile dysfunction treatments.

On 6 May , Pfizer , which manufactures Viagra, told the Associated Press they will begin selling the drug directly to patients on its website.

As of , the U. Food and Drug Administration has approved 15 drug manufacturers to market generic sildenafil in the United States. Seven of these companies are based in India. This is likely to lead to dramatic price reductions. Counterfeit Viagra, despite generally being cheaper, [67] can contain harmful substances or substances that affect how Viagra works, such as blue printer ink, amphetamines , metronidazole , boric acid , and rat poison.

There were 2,, prescriptions for Sildenafil in in England, compared with 1,, in In , Viagra Connect, a particular formulation of Sildenafil marketed by Pfizer, became available for sale without a prescription in the UK, [59] in an attempt to widen availability and reduce demand for counterfeit products. Sildenafil is available as a generic drug in the United States, labelled for pulmonary arterial hypertension. In the United States, Pfizer received two patents for sildenafil: The substance is the same under both trade names.

In , Pfizer filed a patent covering the substance sildenafil and its use to treat cardiovascular diseases. The patent was published in and expired in The patent on Revatio indicated for pulmonary arterial hypertension rather than erectile dysfunction expired in late Generic versions of this low-dose form of sildenafil have been available in the U.

In , Pfizer filed a patent covering the use of sildenafil to treat erectile dysfunction. This patent was published in and will expire in Teva sued to have the latter patent invalidated, but Pfizer prevailed in an August federal district court case. The decision, Teva Canada Ltd. This, in my view, is the key issue in this appeal. Sildenafil was reclassified in New Zealand in so it could be bought over the counter from a pharmacist.

It is thought that this reduced sales over the Internet and was safer as men could be referred for medical advice if appropriate. From Wikipedia, the free encyclopedia. For other uses, see Viagra disambiguation. B No risk in non-human studies. S4 Prescription only CA: P Pharmacy medicines US: British Journal of Clinical Pharmacology.

Division of Pfizer, Inc. Retrieved 5 November Retrieved 1 December Retrieved 21 November Two versions of sildenafil hit the market today". Retrieved 24 November Centers for Medicare and Medicaid Services. The Cochrane Database of Systematic Reviews 1: The Cochrane Database of Systematic Reviews 5: Annals of the Rheumatic Diseases. Commonly-used classes of drugs". Cochrane Database of Systematic Reviews.

Food and Drug Administration. Archived from the original on 22 October The American Journal of Cardiology. Journal of the American College of Cardiology.

Citrate generic name sildenafil viagra

It takes around 40 minutes to show its effect. Retrieved 2 April Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection. One may experience other side effects that are not mentioned above. Journal of the American College of Cardiology.

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Contraindications Viagra Super Force Review is strongly not recommended for young people under 18 years, as well as older men — from and older. In addition to Dapoxetine, it includes Vardenafil. Перевозим продукты питания на специальных газелях-рефрижераторах. It is this time that both active substances act. Хотелось бы отметить, что работаем уже на протяжении долгих лет и нареканий ни разу не было. Possible side effects Physiologically, the effect of Viagra Super Force Review is well tolerated, but, like any chemical Viagra Super Force Review requires compliance with the rules of its use.

The famous Viagra was developed as a remedy for angina, and at first no one paid attention to its unexpected side effect. Scientists switched to it when they realized. Malegra , , 25, 50 mg is a substitute of viagra which cures the ed problem in men. We provide low rate with Free shipping in the USA, UK, France, Australia. Viagra. Best price here. VIAGRA (sildenafil citrate), an oral therapy for erectile dysfunction, is a citrate salt of sildenafil, a selective inhibitor of cyclic.

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